Aortic valve area (AVA), pre-ViV

Continuous, and data-driven tertile split (no fixed clinical cutoff applied).

Raw values by outcome

Died	N=81, mean=0.87 cm2, median=0.80 cm2
Alive	N=144, mean=0.98 cm2, median=0.80 cm2

Comparisons

Comparison	N	Events	β (SE)	Cox HR (95% CI)	Cox p	Log-rank p	Result
Continuous, per 0.1 cm2	225	81	-0.081 (0.040)	0.92 (0.85–1.00)	0.0406	–	Significant
Continuous, per 0.2 cm2	225	81	-0.163 (0.080)	0.85 (0.73–0.99)	0.0406	–	Significant
Top vs bottom tertile (data-driven cutoff)	154	55	-0.589 (0.279)	0.55 (0.32–0.96)	0.0347	0.0325	Significant

Tertile cuts: ≤0.70 cm2 vs >0.90 cm2.

Kaplan–Meier curve

Interactive: select covariates

Every change is sent to the backend, which reruns the Cox model on the full dataset and returns the result (POST /api/multivariate). Listwise deletion: only patients with data for every selected covariate are included.

Post-ViV Echo

Residual AR (any vs none) (presence) Residual AR grade (0-2) (per grade) Residual AR I (mild vs none) (presence) Post-ViV MPG (per 5 mmHg) AVA, post-ViV (per 0.1 cm2) LVEF, post-ViV (per 5%)

Baseline

Age (per 5 yr) Male sex (presence) BMI (per 5 kg/m2) EuroSCORE II (per 1 pt) STS score (per 1 pt) Diabetes (presence) COPD (presence) Atrial fibrillation (presence) Creatinine (per 0.5 mg/dL) eGFR (per 10 mL/min/1.73m2) NYHA class (per class)

Pre-ViV Echo

AS mean gradient, pre-ViV (per 5 mmHg) AVA, pre-ViV (per 0.1 cm2) LVEF, pre-ViV (per 5%) LA volume, pre-ViV (per 10 mL) TR grade, pre-ViV (per grade)

Procedural

TAVI-first (vs SAVR-first) (presence) THV: CoreValve vs SAPIEN family (presence) THV size (per 1 mm) Chimney stenting (presence) General anaesthesia (presence)

Interactive result

N=–, events=–